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Supports normal psychological function – with the help of other B vitamins, biotin can help maintain neurons in the brain. You can find it in animal-based foods, seeds, nuts, nutritional yeast and some vegetables like sweet potatoes Tsao, C. Y. Current trends in the treatment of infantile spasms. Neuropsychiatr.Dis.Treat. 2009;5:289-299. View abstract. Colombo VE, Gerber F, Bronhofer M, Floersheim GL. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy. J Am Acad Dermatol 1990;23:1127-32. [ PubMed abstract]
The bottom line: Biotin can only impact hair growth if there is an existing biotin deficiency. Taking extra biotin supplements does not lead to extra nutrient-based hair growth. 8 How much biotin should I take for hair? No evidence in humans has shown a toxicity of biotin even with high intakes. Because it is water-soluble, any excess amount will leave through the urine. There is no established upper limit or toxic level for biotin. Did You Know?Also, try taking your biotin supplement with food if you haven’t been already, as taking it alone could be causing these side effects.
Kury S, Ramaekers V, Bezieau S, Wolf B. Clinical utility gene card for: Biotinidase deficiency-update 2015. Eur J Hum Genet 2016;24. [ PubMed abstract] Said HM, Redha R, Nylander W. Biotin transport in the human intestine: inhibition by anticonvulsant drugs. Am J Clin Nutr 1989;49:127-31. [ PubMed abstract]
The federal government's 2020–2025 Dietary Guidelines for Americans notes that "Because foods provide an array of nutrients and other components that have benefits for health, nutritional needs should be met primarily through foods. ... In some cases, fortified foods and dietary supplements are useful when it is not possible otherwise to meet needs for one or more nutrients (e.g., during specific life stages such as pregnancy)." Mathais S, Moisset X, Pereira B, et al. Relapses in patients treated with high-dose biotin for progressive multiple sclerosis. Neurotherapeutics. 2020 Sep 22. View abstract. National Institutes of Health; Office of Dietary Supplements. Biotin: Fact Sheet for Health Professionals. https://ods.od.nih.gov/factsheets/Biotin-HealthProfessional/. Accessed 6/10/19. So don’t assume taking biotin supplements will cure hair, skin or nail problems. “If you notice sudden changes in your hair, skin or nails, see your provider,” says Barth. “Don’t self-treat with biotin supplements without knowing the cause.” How much biotin do you need? They contain an impressive 5000ug of biotin along with other nutrients your hair will love like zinc.
Baez-Saldana A, Zendejas-Ruiz I, Revilla-Monsalve C, et al. Effects of biotin on pyruvate carboxylase, acetyl-CoA carboxylase, propionyl-CoA carboxylase, and markers for glucose and lipid homeostasis in type 2 diabetic patients and nondiabetic subjects. Am J Clin Nutr 2004;79:238-43. View abstract. Biotin may also be used in combination with other vitamins in adults and children as a dietary supplement. Pacheco-Alvarez D, Solórzano-Vargas RS, Del Río AL. Biotin in metabolism and its relationship to human disease. Arch Med Res 2002;33:439-47. [ PubMed abstract]Li D, Ferguson A, Cervinski MA, Lynch KL, Kyle PB. AACC Guidance Document on Biotin Interference in Laboratory Tests. J Appl Lab Med. 2020;5(3):575-587. View abstract. Spencer RP and Brody KR. Biotin transport by small intestine of rat, hamster, and other species. Am J Physiol. 1964 Mar;206:653-7. View abstract. Research suggests that women are at risk of a mild biotin deficiency during pregnancy, particularly in the first trimester. 16 But taking high doses of biotin could harm the baby. Choosing a biotin supplement or a multivitamin for hair, skin and nails is often the best bet if you want to make sure you’re getting enough. How much biotin should I take? Magnuson, N. S. and Perryman, L. E. Metabolic defects in severe combined immunodeficiency in man and animals. Comp Biochem.Physiol B 1986;83(4):701-710. View abstract.
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